Neuroimaging: Current role in detecting pre‐motor Parkinson's disease
Identifieur interne : 001310 ( Main/Exploration ); précédent : 001309; suivant : 001311Neuroimaging: Current role in detecting pre‐motor Parkinson's disease
Auteurs : Jana Godau [Allemagne] ; Anna Hussl [Autriche] ; Praween Lolekha [Canada] ; A. Jon Stoessl [Canada] ; Klaus Seppi [Autriche]Source :
- [ 0885-3185 ]
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Convergent evidence suggests a pre‐motor period in Parkinson's disease (PD) during which typical motor symptoms have not yet developed although dopaminergic neurons in the substantia nigra have started to degenerate. Advances in different neuroimaging techniques have allowed the detection of functional and structural changes in early PD. This review summarizes the state of the art knowledge concerning structural neuroimaging techniques including magnetic resonance imaging (MRI) and transcranial B‐mode‐Doppler‐sonography (TCS) as well as functional neuroimaging techniques using radiotracer imaging (RTI) with different radioligands in detecting pre‐motor PD. © 2012 Movement Disorder Society
Url:
DOI: 10.1002/mds.24976
Affiliations:
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Jon Stoessl</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Pacific Parkinson's Research Centre, University of British Columbia and Vancouver Coastal Health, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Austria, Anichstrasse 35, A‐6020 Innsbruck</wicri:regionArea><wicri:noRegion>A‐6020 Innsbruck</wicri:noRegion></affiliation></author></analytic><series><idno type="ISSN">0885-3185</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Nervous system diseases</term><term>Nuclear magnetic resonance imaging</term><term>Parkinson disease</term><term>Photon</term><term>Positron emission tomography</term><term>Single photon emission tomography</term><term>Ultrasound</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Imagerie RMN</term><term>Maladie de Parkinson</term><term>Pathologie du système nerveux</term><term>Photon</term><term>Tomographie par émission de positons</term><term>Tomoscintigraphie émission monophotonique</term><term>Ultrason</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Convergent evidence suggests a pre‐motor period in Parkinson's disease (PD) during which typical motor symptoms have not yet developed although dopaminergic neurons in the substantia nigra have started to degenerate. Advances in different neuroimaging techniques have allowed the detection of functional and structural changes in early PD. This review summarizes the state of the art knowledge concerning structural neuroimaging techniques including magnetic resonance imaging (MRI) and transcranial B‐mode‐Doppler‐sonography (TCS) as well as functional neuroimaging techniques using radiotracer imaging (RTI) with different radioligands in detecting pre‐motor PD. © 2012 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Canada</li></country><region><li>Bade-Wurtemberg</li><li>District de Tübingen</li></region><settlement><li>Tübingen</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Godau, Jana" sort="Godau, Jana" uniqKey="Godau J" first="Jana" last="Godau">Jana Godau</name></region></country><country name="Autriche"><noRegion><name sortKey="Hussl, Anna" sort="Hussl, Anna" uniqKey="Hussl A" first="Anna" last="Hussl">Anna Hussl</name></noRegion><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name></country><country name="Canada"><noRegion><name sortKey="Lolekha, Praween" sort="Lolekha, Praween" uniqKey="Lolekha P" first="Praween" last="Lolekha">Praween Lolekha</name></noRegion><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A. 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